KRAS G12C inhibitor 38

Catalog No.: A63693
Anti-cancer Agent
KRAS G12C inhibitor 38 is a selective inhibitor targeting the mutant form of KRAS G12C, an essential component of intracellular signaling pathways involved in cellular growth and proliferation. This compound exhibits significant anti-cancer activity and is primarily applied in research focused on KRAS G12C-driven malignancies. Its utilization can aid in the exploration and understanding of therapeutic strategies against cancers characterized by KRAS mutations.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12C inhibitor 38 is a selective inhibitor targeting the mutant form of KRAS G12C, an essential component of intracellular signaling pathways involved in cellular growth and proliferation. This compound exhibits significant anti-cancer activity and is primarily applied in research focused on KRAS G12C-driven malignancies. Its utilization can aid in the exploration and understanding of therapeutic strategies against cancers characterized by KRAS mutations.
Product Information
Catalog NumA63693
FormulaC38H43F3N8O2
Molecular Weight700.80
CAS Number2660129-56-4
SMILESO=C(N1CC2(CCN(CC2)C3=NC(N4CC(C4)N5CCCC5)=NC6=C(C(C7=C8C=NNC8=CC=C7C)=C(C9CC9)C=C63)OCC(F)(F)F)C1)C=C
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