• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

KRAS G12C Ligand-Linker Conjugates 1

Catalog No.: A63694
Target Protein Ligand-Linker Conjugate
KRAS G12C Ligand-Linker Conjugates 1 is a conjugate formed from the KRAS G12C ligand and a linker moiety. This compound is designed to facilitate the targeted degradation of KRAS G12C proteins through the synthesis of PROTAC YF135. It serves as a valuable tool for studying KRAS-related signaling pathways and exploring therapeutic strategies in KRAS-driven cancers.
KRAS G12C Ligand-Linker Conjugates 1 3033236-98-2 Target Protein Ligand-Linker Conjugate
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Notify me when this product is in stock
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12C Ligand-Linker Conjugates 1 is a conjugate formed from the KRAS G12C ligand and a linker moiety. This compound is designed to facilitate the targeted degradation of KRAS G12C proteins through the synthesis of PROTAC YF135. It serves as a valuable tool for studying KRAS-related signaling pathways and exploring therapeutic strategies in KRAS-driven cancers.
Product Information
Catalog NumA63694
FormulaC45H55ClN8O5
Molecular Weight823.42
CAS Number3033236-98-2
SMILESO=C(CCOCCCN1CCC[C@H]1COC2=NC3=C(C(N4CCN([C@H](C4)CC#N)C(/C(C#N)=C/C5CC5)=O)=N2)CCN(C3)C6=CC=CC7=C6C(Cl)=CC=C7)OC(C)(C)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Cell Cycle > Ras