KRAS G12D inhibitor 12

Catalog No.: A63632
Anti-cancer Agent
KRAS G12D inhibitor 12 specifically targets the KRAS G12D mutation, a critical player in cellular signaling pathways associated with tumorigenesis. This compound exhibits potent anti-cancer activity, making it a valuable tool for researchers investigating KRAS G12D-mediated cancers. Its application includes evaluating therapeutic strategies and understanding the molecular mechanisms of oncogenic signaling in various cancer types.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12D inhibitor 12 specifically targets the KRAS G12D mutation, a critical player in cellular signaling pathways associated with tumorigenesis. This compound exhibits potent anti-cancer activity, making it a valuable tool for researchers investigating KRAS G12D-mediated cancers. Its application includes evaluating therapeutic strategies and understanding the molecular mechanisms of oncogenic signaling in various cancer types.
Product Information
Catalog NumA63632
FormulaC23H21ClFN5O3
Molecular Weight469.90
CAS Number2648552-54-7
SMILESO=C([C@@H]1CN1)N2CCN3C4=NC=NC5=C4C(OCC[C@@H]3C2)=C(C(C6=C(C=CC=C6O)F)=C5)Cl
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