KRAS G12D inhibitor 24

Catalog No.: A63639
KRAS G12D Inhibitor
KRAS G12D inhibitor 24 is a potent inhibitor of the KRAS G12D mutant, exhibiting an IC50 of 0.004 μM. This compound demonstrates significant oral bioactivity, making it suitable for in vivo studies. Its primary applications include exploring therapeutic avenues in cancer research, specifically for tumors driven by KRAS G12D mutations.
Grouped product items
Size Price Stock Qty
25mg
$2,285.00
In stock
50mg
$2,935.00
In stock
100mg
$3,920.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12D inhibitor 24 is a potent inhibitor of the KRAS G12D mutant, exhibiting an IC50 of 0.004 μM. This compound demonstrates significant oral bioactivity, making it suitable for in vivo studies. Its primary applications include exploring therapeutic avenues in cancer research, specifically for tumors driven by KRAS G12D mutations.
Product Information
Catalog NumA63639
FormulaC34H33F3N6O2
Molecular Weight614.66
CAS Number3033701-29-7
SMILESOC1=CC(C2=C(F)C3=NC(OC[C@]4(C)CN(C)CC/C4=C\F)=NC(N5C[C@H](N6)CC[C@H]6C5)=C3C=N2)=C7C(C#C)=C(F)C=CC7=C1
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