KRAS G12D inhibitor 1

Name: KRAS G12D inhibitor 1
Brand: Adooq Bioscience
SKU: A63577
Rating: 5 (288 reviews)

Catalog No.: A63577

KRAS G12D Inhibitor

KRAS G12D Inhibitor 1 is a potent inhibitor targeting the KRAS G12D mutant with an IC50 of 0.4 nM. It effectively inhibits KRAS G12D-mediated ERK phosphorylation, exhibiting an IC50 of 0.8 nM. This compound is valuable in research focused on cancers driven by KRAS G12D mutations, including pancreatic ductal adenocarcinoma and colorectal cancer.

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KRAS G12D inhibitor 1 2621928-43-4 KRAS G12D Inhibitor

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Grouped product items
Size	Price	Stock
1mg	$545.00	In stock
5mg	$1,230.00	In stock
10mg	$2,140.00	In stock
25mg	$10,500.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	KRAS G12D Inhibitor 1 is a potent inhibitor targeting the KRAS G12D mutant with an IC50 of 0.4 nM. It effectively inhibits KRAS G12D-mediated ERK phosphorylation, exhibiting an IC50 of 0.8 nM. This compound is valuable in research focused on cancers driven by KRAS G12D mutations, including pancreatic ductal adenocarcinoma and colorectal cancer.

Product Information

Catalog Num	A63577
Formula	C33H32F2N6O2
Molecular Weight	582.64
CAS Number	2621928-43-4
SMILES	OC1=CC(C2=C(F)C3=NC(OC[C@@]45CCCN4C[C@H](F)C5)=NC(N6C[C@H]7N[C@H](CC7)C6)=C3C=N2)=C8C(C#C)=CC=CC8=C1

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