KRAS G12D inhibitor 3 is a selective inhibitor targeting the KRAS G12D mutant with an IC50 of less than 500 nM. It exhibits significant antitumor activity, making it relevant for cancer research focused on KRAS-driven tumors. Additionally, this compound functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules, facilitating various bioconjugation applications in molecular biology.
KRAS G12D inhibitor 3 is a selective inhibitor targeting the KRAS G12D mutant with an IC50 of less than 500 nM. It exhibits significant antitumor activity, making it relevant for cancer research focused on KRAS-driven tumors. Additionally, this compound functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules, facilitating various bioconjugation applications in molecular biology.
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