KRAS inhibitor-12 is a potent inhibitor specifically targeting the KRAS G12C mutation, exhibiting an IC50 of 0.537 µM. This compound demonstrates effective inhibition of phosphorylated ERK in MIA PaCA-2 and A549 cells, with IC50 values of 1.3 µM and 3.7 µM, respectively. KRAS inhibitor-12 is a valuable tool for investigating therapeutic strategies in pancreatic, colorectal, and lung cancers.
KRAS inhibitor-12 is a potent inhibitor specifically targeting the KRAS G12C mutation, exhibiting an IC50 of 0.537 µM. This compound demonstrates effective inhibition of phosphorylated ERK in MIA PaCA-2 and A549 cells, with IC50 values of 1.3 µM and 3.7 µM, respectively. KRAS inhibitor-12 is a valuable tool for investigating therapeutic strategies in pancreatic, colorectal, and lung cancers.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
