L-770644

Catalog No.: A58827
β3 Adrenergic Receptor Agonist
L-770644 is a potent and selective agonist of the human β3 adrenergic receptor, with an EC50 of 13 nM, demonstrating oral bioactivity. This compound is primarily utilized in research exploring metabolic disorders, obesity, and diabetes, where modulation of β3 receptor activity may contribute to therapeutic strategies. Its specificity for the β3 receptor makes it a valuable tool for studying adrenergic signaling pathways and their physiological effects.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-770644 is a potent and selective agonist of the human β3 adrenergic receptor, with an EC50 of 13 nM, demonstrating oral bioactivity. This compound is primarily utilized in research exploring metabolic disorders, obesity, and diabetes, where modulation of β3 receptor activity may contribute to therapeutic strategies. Its specificity for the β3 receptor makes it a valuable tool for studying adrenergic signaling pathways and their physiological effects.
Product Information
Catalog NumA58827
FormulaC30H37N7O4S
Molecular Weight591.72
CAS Number173901-95-6
SMILESO=C1N(C2=CC=C(C=C2)S(NC3=CC=C(C=C3)CCNC[C@@H](C4=CN=CC=C4)O)(=O)=O)N=NN1CCCC5CCCC5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2