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L-Pyroglutamic acid 7-amido-4-methylcoumarin

PGP-1 Fluorogenic Substrate

L-Pyroglutamic acid 7-amido-4-methylcoumarin serves as a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1). This compound exhibits biological activity by enabling the detection of PGP-1 enzymatic activity through fluorescence development. It is primarily utilized in biochemical assays for characterizing the enzyme's function and studying related pathways in research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	66642-36-2
Applications	PGP-1 Fluorogenic Substrate
Formula	C₁₅H₁₄N₂O₄
Molecular Weight	286.28
SMILES	CC(C1=CC=C(NC([C@H]2NC(CC2)=O)=O)C=C1O3)=CC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.