Fig. 1 · Structure

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LasR-IN-1

LasR Inhibitor

LasR-IN-1 is a potent inhibitor of the LasR quorum-sensing receptor in Pseudomonas aeruginosa. This compound demonstrates significant antibacterial activity, exhibiting a minimum inhibitory concentration (MIC) of 28.13 μM against P. aeruginosa. LasR-IN-1 is valuable for research applications focused on modulating bacterial communication and exploring novel strategies for combating antibiotic resistance in Gram-negative bacteria.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3033530-75-2
Applications LasR Inhibitor
Formula C23H21N3O2
Molecular Weight 371.43
SMILES
O=C(NC1=CC=C(C)C=C1)COC2=CC=C(C3=NC4=CC(C)=CC=C4N3)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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