Fig. 1 · Structure

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LasR-IN-2

LasR Inhibitor

LasR-IN-2 is a specific inhibitor of the LasR receptor, which plays a crucial role in bacterial quorum sensing. This compound is effective in disrupting virulence factor production in Pseudomonas aeruginosa, making it instrumental in the study of bacterial infections, particularly in relation to neutropenia, severe burns, and chronic lung disease in cystic fibrosis. LasR-IN-2 serves as a valuable tool for exploring therapeutic strategies against multidrug-resistant bacterial pathogens.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3033530-61-6
Applications LasR Inhibitor
Formula C21H16ClN3O2
Molecular Weight 377.82
SMILES
O=C(NC1=CC=CC=C1)COC2=CC=C(C3=NC4=CC(Cl)=CC=C4N3)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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