LDN-193189 2HCl

Name: LDN-193189 2HCl
Brand: Adooq Bioscience
SKU: A22307
Rating: 5 (288 reviews)

Catalog No.: A22307

BMP signaling inhibitor

LDN193189 HCl (DM-3189) is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.

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LDN-193189 2HCl 1435934-00-1 BMP signaling inhibitor

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Grouped product items
Size	Price	Stock
5mg	$60.00	In stock
10mg	$80.00	In stock
25mg	$140.00	In stock
50mg	$230.00	In stock
100mg	$345.00	In stock
500mg	$830.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	LDN193189 HCl (DM-3189) is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.

Product Information

Catalog Num	A22307
Formula	C25H24Cl2N6
Molecular Weight	479.4
CAS Number	1435934-00-1
SMILES	N1(C2=CC=C(C(C=N3)=CN4C3=C(C5=CC=NC6=C5C=CC=C6)C=N4)C=C2)CCNCC1.Cl.Cl
Synonyms	DM-3189 2HCl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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