Phospholipids

Cat. No.

A27013

CAS No.

154436-49-4

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe

Synonyms: 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid featuring stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. This compound is generated through the oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe via the enzyme 15-lipoxygenase. It is shown to enhance ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts when treated with the GPX4 inhibitor RSL3. Its unique properties make it a valuable reagent for studying ferroptosis and lipid metabolism in cellular models.

Cat. No.

A76342

CAS No.

163751-35-7

rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate

Rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate is a phospholipid compound that acts as an inhibitor of Protein Kinase C. This reagent is pertinent for studies investigating lipid signaling pathways and cellular processes influenced by kinase activity. Its role in modulating protein interactions makes it significant for research in cellular signaling and membrane biochemistry.

Cat. No.

B21862

CAS No.

137319-25-6

Echiguanine A

Echiguanine A is a potent inhibitor of phosphatidylinositol 4-kinase II alpha (PI4KIIα), demonstrating an IC50 of 0.04 μg/mL. This compound effectively inhibits the enzymatic activity of phosphatidylinositol 4-kinase in cell membrane extracts, making it a valuable tool for studying lipid signaling pathways. Echiguanine A is particularly relevant in cancer research, where PI4KIIα modulation may influence tumor cell growth and proliferation.