Lomitapide-d8

Catalog No.: B14503
Stable Isotope
Lomitapide-d8 is a deuterium-labeled analog of Lomitapide, a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro. This stable isotope derivative can be utilized in metabolic studies and tracer experiments, providing insights into lipid metabolism and the role of MTP in disease. Lomitapide-d8 is particularly valuable in pharmacokinetic research and mass spectrometry applications.
Grouped product items
Size Price Stock Qty
1mg
$655.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLomitapide-d8 is a deuterium-labeled analog of Lomitapide, a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro. This stable isotope derivative can be utilized in metabolic studies and tracer experiments, providing insights into lipid metabolism and the role of MTP in disease. Lomitapide-d8 is particularly valuable in pharmacokinetic research and mass spectrometry applications.
Product Information
Catalog NumB14503
FormulaC39H29D8F6N3O2
Molecular Weight701.77
CAS Number2459377-96-7
SMILESO=C(C1(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F
SynonymsAEGR-733-d8; BMS-201038-d8
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