Fig. 1 · Structure
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LpxC-IN-13
LpxC Inhibitor
LpxC-IN-13 is a potent LpxC inhibitor, exhibiting an IC50 of 18.06 nM. This compound effectively disrupts the biosynthesis of lipid A, a crucial component of the outer membrane of Gram-negative bacteria, thereby providing a valuable tool in combating Gram-negative bacterial infections. LpxC-IN-13 is suitable for research applications focused on antibiotic development and understanding bacterial resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3033881-14-7 |
| Applications | LpxC Inhibitor |
| Formula | C25H28N4O3 |
| Molecular Weight | 432.51 |
| SMILES | C[C@@H](C1=NC=CN1CC2=NOC(C3=CC=C(C=C3)C#C[C@H]4C[C@@H](C4)N5CCOCC5)=C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.