Fig. 1 · Structure
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LpxC-IN-9
LpxC Inhibitor
LpxC-IN-9 is a potent inhibitor of LpxC, a key enzyme involved in lipid A biosynthesis in Gram-negative bacteria. This compound exhibits significant antibacterial activity and potential hypotensive effects. Additionally, LpxC-IN-9 serves as a click chemistry reagent due to its alkyne functionality, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This makes it a valuable tool for bioconjugation and chemical biology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2756125-46-7 |
| Applications | LpxC Inhibitor |
| Formula | C23H25N5O3S |
| Molecular Weight | 451.54 |
| SMILES | CS[C@H](N(C=O)O)CN1N=NC2=C1C=CC(C#CC3=CC=C(C=C3)CN4CCOCC4)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.