LRH-1 antagonist-1 is a selective antagonist of Liver Receptor Homolog-1 (LRH-1) with a Kd of 1.8 μM. This compound effectively inhibits the transcriptional activity of LRH-1, leading to reduced expression of G0S2 and subsequent inhibition of proliferation in LRH-1-positive cancer cells. It is suitable for research applications in pancreatic, colon, and breast cancer studies, where targeting LRH-1 may provide valuable insights into tumor growth and progression.
LRH-1 antagonist-1 is a selective antagonist of Liver Receptor Homolog-1 (LRH-1) with a Kd of 1.8 μM. This compound effectively inhibits the transcriptional activity of LRH-1, leading to reduced expression of G0S2 and subsequent inhibition of proliferation in LRH-1-positive cancer cells. It is suitable for research applications in pancreatic, colon, and breast cancer studies, where targeting LRH-1 may provide valuable insights into tumor growth and progression.
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