GSK8470 is a potent LRH-1 and SF-1 agonist, with EC50 values of 0.43 μM and 0.054 μM, respectively. This compound enhances the expression of small heterodimer chaperones (SHPs), a critical target gene regulated by LRH-1, in hepatocytes. GSK8470 is valuable for research applications involving the modulation of nuclear hormone receptor signaling pathways and related metabolic processes.
GSK8470 is a potent LRH-1 and SF-1 agonist, with EC50 values of 0.43 μM and 0.054 μM, respectively. This compound enhances the expression of small heterodimer chaperones (SHPs), a critical target gene regulated by LRH-1, in hepatocytes. GSK8470 is valuable for research applications involving the modulation of nuclear hormone receptor signaling pathways and related metabolic processes.
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