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Lubiprostone-d7

Catalog No.: A25520
Stable Isotope
Lubiprostone-d7 is a deuterated form of Lubiprostone, targeting the CIC-2/CFTR pathways to enhance intestinal fluid secretion. This compound is notable for its ability to inhibit myeloperoxidase (MPO) activity and downregulate the expression of iNOS and TNFα induced by Indomethacin. Lubiprostone-d7 is primarily utilized in research applications focused on chronic constipation and gastrointestinal disorders, providing a stable isotope for in-depth biochemical analysis.
Lubiprostone-d7 1217675-13-2 Stable Isotope
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLubiprostone-d7 is a deuterated form of Lubiprostone, targeting the CIC-2/CFTR pathways to enhance intestinal fluid secretion. This compound is notable for its ability to inhibit myeloperoxidase (MPO) activity and downregulate the expression of iNOS and TNFα induced by Indomethacin. Lubiprostone-d7 is primarily utilized in research applications focused on chronic constipation and gastrointestinal disorders, providing a stable isotope for in-depth biochemical analysis.
Product Information
Catalog NumA25520
FormulaC20H25D7F2O5
Molecular Weight397.51
CAS Number1217675-13-2
SMILESC(CC(C(CC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])(F)F)=O)[C@@H]1[C@@H](CCCCCCC(O)=O)C(=O)C[C@H]1O
SynonymsRU-0211-d7; SPI-0211-d7
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Isotope-Labeled Compounds