LY-195448 hydrochloride is a phenethanolamine that targets cellular processes during the metaphase of the cell cycle, exhibiting notable anti-tumor activity in various murine tumor models. This compound has shown a favorable safety profile, lacking many common side effects associated with conventional cancer therapies, such as myelosuppression and gastrointestinal toxicity. In phase I clinical trials, LY-195448 hydrochloride resulted in mild and reversible side effects, including hypotension, tachycardia, and tremors, making it a promising candidate in cancer research applications.
LY-195448 hydrochloride is a phenethanolamine that targets cellular processes during the metaphase of the cell cycle, exhibiting notable anti-tumor activity in various murine tumor models. This compound has shown a favorable safety profile, lacking many common side effects associated with conventional cancer therapies, such as myelosuppression and gastrointestinal toxicity. In phase I clinical trials, LY-195448 hydrochloride resulted in mild and reversible side effects, including hypotension, tachycardia, and tremors, making it a promising candidate in cancer research applications.
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