LY262691

Catalog No.: A59686
CCK-B Antagonist
LY262691 is a selective antagonist of the cholecystokinin B (CCK-B) receptor, known for its antipsychotic properties. This compound effectively reduces the activity of spontaneously firing A9 and A10 dopamine neurons, making it a valuable tool in antipsychotic research. Its mechanism offers insights into the modulation of dopaminergic signaling pathways related to psychiatric disorders.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY262691 is a selective antagonist of the cholecystokinin B (CCK-B) receptor, known for its antipsychotic properties. This compound effectively reduces the activity of spontaneously firing A9 and A10 dopamine neurons, making it a valuable tool in antipsychotic research. Its mechanism offers insights into the modulation of dopaminergic signaling pathways related to psychiatric disorders.
Product Information
Catalog NumA59686
FormulaC22H18BrN3O2
Molecular Weight436.30
CAS Number138932-35-1
SMILESBrC(C=C1)=CC=C1NC(N2[C@@H](C3=CC=CC=C3)[C@H](C4=CC=CC=C4)C(N2)=O)=O
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