LY288513

Catalog No.: A59706
CCK-B Receptor Antagonist
LY288513 is a selective non-peptide antagonist of the cholecystokinin B (CCK-B) receptor, exhibiting an IC50 value of 16 nM. It has been demonstrated to produce anxiolytic-like effects in murine models, making it a valuable tool for research in anxiety disorders and related neurobiological studies. Its specificity for the CCK-B receptor allows for targeted investigation into the mechanisms underlying anxiety and stress responses.
Grouped product items
Size Price Stock Qty
1mg
$200.00
In stock
5mg
$515.00
In stock
10mg
$845.00
In stock
50mg
$5,050.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY288513 is a selective non-peptide antagonist of the cholecystokinin B (CCK-B) receptor, exhibiting an IC50 value of 16 nM. It has been demonstrated to produce anxiolytic-like effects in murine models, making it a valuable tool for research in anxiety disorders and related neurobiological studies. Its specificity for the CCK-B receptor allows for targeted investigation into the mechanisms underlying anxiety and stress responses.
Product Information
Catalog NumA59706
FormulaC22H18BrN3O2
Molecular Weight436.30
CAS Number147523-65-7
SMILESO=C(N1NC([C@@H](C2=CC=CC=C2)[C@@H]1C3=CC=CC=C3)=O)NC4=CC=C(Br)C=C4
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