LY573636 (Tasisulam)

Name: LY573636 (Tasisulam)
Brand: Adooq Bioscience
SKU: A13070
Rating: 100 (2 reviews)

Catalog No.: A13070

Apoptosis inducer

Product Citations (2)

LY573636 (Tasisulam) Chemical Structure

CAS NO. 519055-62-0

LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.

Availability: In stock

Package	Price	Qty
5 mg	$40.00
10 mg	$60.00
25 mg	$120.00
50 mg	$180.00
10mM * 1mL in DMSO	$92.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq LY573636 (Tasisulam)

Ting TC, .et al. Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15, Cell Rep, 2019, Nov 5;29(6):1499-1510.e6 PMID: 31693891
Ting Han, .et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15, Science, 2017, Apr 28;356(6336). pii: eaal3755 PMID: 28302793

Biological Activity

Targets

Caspase

Solubility *

In vitro	DMSO	73 mg/mL (175.85 mM)
	Water	Insoluble
	Ethanol	73 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.09 mL	120.45 mL	240.9 mL
0.5 mM	4.82 mL	24.09 mL	48.18 mL
1 mM	2.41 mL	12.05 mL	24.09 mL
5 mM	0.48 mL	2.41 mL	4.82 mL

*The above data is based on the productmolecular weight 415.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A13070
Actions	Inducer
CAS No.	519055-62-0
Formula	C11H6BrCl2NO3S2
M. Wt	415.11
Purity	>98%
Synonyms	LY 573636, LY-573636
SMILES	C1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.