LY573636 (Tasisulam)

Catalog No.: A13070

Apoptosis inducer

LY573636 (Tasisulam)

LY573636 (Tasisulam) Chemical Structure

CAS NO. 519055-62-0

LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$60.00
25 mg
$120.00
50 mg
$180.00
10mM * 1mL in DMSO
$92.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Ting Han, .et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15, Science, 2017, Apr 28;356(6336). pii: eaal3755 PMID: 28302793

Biological Activity

LY573636 is a potent anti-tumor agent, which causes growth arrest and apoptosis of a variety of human solid tumors in vitro and in vivo. LY573636-induced apoptosis occurs by a mitochondrial-targeted mechanism.
Targets
Caspase
In vitro DMSO 83 mg/mL (199.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 83 mg/mL (199.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.09 mL 120.45 mL 240.9 mL
0.5 mM 4.82 mL 24.09 mL 48.18 mL
1 mM 2.41 mL 12.05 mL 24.09 mL
5 mM 0.48 mL 2.41 mL 4.82 mL

*The above data is based on the productmolecular weight 415.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13070
Actions Inducer
M. Wt 415.11
Formula C11H6BrCl2NO3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 519055-62-0
Synonyms LY 573636, LY-573636
SMILES C1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br

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