Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable linker specifically designed for use in the development of antibody-drug conjugates (ADCs). This compound features an azide group that facilitates its application in click chemistry, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it versatile for conjugating with DBCO or BCN-containing compounds. It is an essential tool for enhancing the delivery and efficacy of therapeutic agents in targeted cancer therapies.
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable linker specifically designed for use in the development of antibody-drug conjugates (ADCs). This compound features an azide group that facilitates its application in click chemistry, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it versatile for conjugating with DBCO or BCN-containing compounds. It is an essential tool for enhancing the delivery and efficacy of therapeutic agents in targeted cancer therapies.
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