Fig. 1 · Structure

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M-2420

Fluorogenic Substrate

M-2420 is a fluorogenic substrate designed to target the β-secretase site of the Swedish mutation of amyloid precursor protein (APP). This compound exhibits key biological activity by facilitating the detection and quantification of β-secretase activity, which is crucial for understanding amyloidogenic processes in Alzheimer’s disease. M-2420 is suitable for research applications focused on neurodegenerative diseases and protein cleavage mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 310427-95-3
Applications Fluorogenic Substrate
Formula C70H91N15O27
Molecular Weight 1574.56
SMILES
O=[N+](C(C=C1)=CC([N+]([O-])=O)=C1CC(NCCCC[C@@H](C(N)=O)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CO)NC(CC(C3=CC=C(OC)C=C3O4)=CC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[O-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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