m-PEG6-azide is a non-cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This reagent features an azide functional group, enabling it to participate in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, m-PEG6-azide can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds possessing DBCO or BCN groups, making it a versatile tool for ADC development and other bioconjugation applications.
m-PEG6-azide is a non-cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This reagent features an azide functional group, enabling it to participate in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, m-PEG6-azide can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds possessing DBCO or BCN groups, making it a versatile tool for ADC development and other bioconjugation applications.
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