Mal-Sulfo-DBCO

Catalog No.: A43051
ADC Linker
Mal-Sulfo-DBCO is a cleavable linker designed for use in antibody-drug conjugate (ADC) synthesis. Featuring a DBCO moiety, it facilitates the efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reaction with azide-containing compounds. This property makes Mal-Sulfo-DBCO valuable for precise conjugation in targeted drug delivery applications, enhancing therapeutic efficacy while minimizing off-target effects.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-Sulfo-DBCO is a cleavable linker designed for use in antibody-drug conjugate (ADC) synthesis. Featuring a DBCO moiety, it facilitates the efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reaction with azide-containing compounds. This property makes Mal-Sulfo-DBCO valuable for precise conjugation in targeted drug delivery applications, enhancing therapeutic efficacy while minimizing off-target effects.
Product Information
Catalog NumA43051
FormulaC28H26N4O8S
Molecular Weight578.59
CAS Number2028281-86-7
SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(C(S(=O)(O)=O)CNC(CCN(C4=O)C(C=C4)=O)=O)=O
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