Mavacamten-d6 is a deuterium-labeled analog of Mavacamten, a selective modulator of cardiac myosin. It demonstrates inhibitory activity with IC50 values of 490 nM for bovine cardiac myosin and 711 nM for human cardiac myosin. This stable isotope form is useful in pharmacokinetic studies and metabolic research to trace and quantify drug behavior in biological systems.
Mavacamten-d6 is a deuterium-labeled analog of Mavacamten, a selective modulator of cardiac myosin. It demonstrates inhibitory activity with IC50 values of 490 nM for bovine cardiac myosin and 711 nM for human cardiac myosin. This stable isotope form is useful in pharmacokinetic studies and metabolic research to trace and quantify drug behavior in biological systems.
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