Mazapertine is an orally active antipsychotic agent primarily targeting dopamine D2, D3, and D4 receptors with high affinity (Ki values < 3 nM). Additionally, it exhibits significant binding to serotonin 5-HT1A receptors (Ki = 1.7 nM) and α1-adrenergic receptors (Ki = 1.3 nM). This compound is valuable for research into neurological diseases, particularly in the context of antipsychotic drug development and neuropharmacology studies.
Mazapertine is an orally active antipsychotic agent primarily targeting dopamine D2, D3, and D4 receptors with high affinity (Ki values < 3 nM). Additionally, it exhibits significant binding to serotonin 5-HT1A receptors (Ki = 1.7 nM) and α1-adrenergic receptors (Ki = 1.3 nM). This compound is valuable for research into neurological diseases, particularly in the context of antipsychotic drug development and neuropharmacology studies.
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