MC-Sq-Cit-PAB-Dolastatin10

Catalog No.: A18518

tubulin polymerization inhibitor

MC-Sq-Cit-PAB-Dolastatin10

MC-Sq-Cit-PAB-Dolastatin10 Chemical Structure

CAS NO. 1941168-65-5

MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.47 mL 37.35 mL 74.7 mL
0.5 mM 1.49 mL 7.47 mL 14.94 mL
1 mM 0.75 mL 3.73 mL 7.47 mL
5 mM 0.15 mL 0.75 mL 1.49 mL

*The above data is based on the productmolecular weight 1338.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18518
Actions Inhibitor
CAS No. 1941168-65-5
Formula C70H105N12O12S
M. Wt 1338.72
Purity >98%
SMILES C[N+]([[email protected]](C(N[[email protected]](C(N([[email protected]@H]([[email protected]@H](C)CC)[[email protected]](OC)CC(N1[[email protected]]([[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C2=NC=CS2)CC3=CC=CC=C3)=O)CCC1)=O)C)=O)C(C)C)=O)C(C)C)(CC4=CC=C(NC([[email protected]@H](NC(C5(C(NCCCCCN6C(C=CC6=O)=O)=O)CCC5)=O)CCCNC(N)=O)=O)C=C4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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