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MC-Sq-Cit-PAB-Dolastatin10

Catalog No.: A18518
tubulin polymerization inhibitor
MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
MC-Sq-Cit-PAB-Dolastatin10
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Size Price Stock Qty
1mg
$320.00
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5mg
$960.00
In stock
10mg
$1,600.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
Targets
Target Value
Product Information
Catalog Num A18518
Formula C70H105N12O12S
Molecular Weight 1338.72
CAS Number 1941168-65-5
SMILES C[N+]([C@H](C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C2=NC=CS2)CC3=CC=CC=C3)=O)CCC1)=O)C)=O)C(C)C)=O)C(C)C)(CC4=CC=C(NC([C@@H](NC(C5(C(NCCCCCN6C(C=CC6=O)=O)=O)CCC5)=O)CCCNC(N)=O)=O)C=C4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC
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