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$0.00 Biological Activity
MC-Val-Cit-PAB-Auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.77 mL | 38.83 mL | 77.66 mL |
| 0.5 mM | 1.55 mL | 7.77 mL | 15.53 mL |
| 1 mM | 0.78 mL | 3.88 mL | 7.77 mL |
| 5 mM | 0.16 mL | 0.78 mL | 1.55 mL |
*The above data is based on the productmolecular weight 1287.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18508 |
|---|---|
| CAS No. | 2055896-77-8 |
| Formula | C68H108N11O13 |
| M. Wt | 1287.65 |
| Purity | >98% |
| SMILES | O[[email protected]@H](C1=CC=CC=C1)[[email protected]@H](C)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]@]([[email protected]@H](C)CC)([H])N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)[N+](C)(C)CC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)=O)=O)OC)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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