MC-Val-Cit-PAB-Auristatin E

Catalog No.: A18508

MC-Val-Cit-PAB-Auristatin E

MC-Val-Cit-PAB-Auristatin E Chemical Structure

CAS NO. 2055896-77-8

MC-Val-Cit-PAB-Auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

MC-Val-Cit-PAB-Auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.77 mL 38.83 mL 77.66 mL
0.5 mM 1.55 mL 7.77 mL 15.53 mL
1 mM 0.78 mL 3.88 mL 7.77 mL
5 mM 0.16 mL 0.78 mL 1.55 mL

*The above data is based on the productmolecular weight 1287.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18508
CAS No. 2055896-77-8
Formula C68H108N11O13
M. Wt 1287.65
Purity >98%
SMILES O[[email protected]@H](C1=CC=CC=C1)[[email protected]@H](C)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]@]([[email protected]@H](C)CC)([H])N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)[N+](C)(C)CC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)=O)=O)OC)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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