MC-VC-PABC-DNA31

Catalog No.: A18511

MC-VC-PABC-DNA31

MC-VC-PABC-DNA31 Chemical Structure

CAS NO. 1639352-03-6

MC-VC-PABC-DNA31 is a drug-linker conjugate for ADC with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

MC-VC-PABC-DNA31 is a drug-linker conjugate for ADC with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.69 mL 33.43 mL 66.86 mL
0.5 mM 1.34 mL 6.69 mL 13.37 mL
1 mM 0.67 mL 3.34 mL 6.69 mL
5 mM 0.13 mL 0.67 mL 1.34 mL

*The above data is based on the productmolecular weight 1495.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18511
CAS No. 1639352-03-6
Formula C77H94N10O21
M. Wt 1495.62
Purity >98%
SMILES O=C([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN1C(C=CC1=O)=O)=O)=O)NC2=CC=C(COC(NC3CCN(C4=CC(OC(C5=N6)=C(NC(/C(C)=C\C=C\[[email protected]](C)[[email protected]]([O])[[email protected]@H](C)[[email protected]@H](O)[[email protected]@H](C)[[email protected]](OC(C)=O)[[email protected]](C)[[email protected]@H](OC)/C=C/O7)=O)C(C8=C([O])C(C)=C(O[[email protected]@]7(C)C9=O)C9=C85)=O)=C6C(O)=C4)CC3)=O)C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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