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Mca-PLAQAV-Dpa-RSSSR-NH2

Catalog No.: A76832
Fluorescent Peptide
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide designed as a substrate for TNF-α converting enzyme (TACE; ADAM17), ADAM9, and ADAM10. This peptide utilizes fluorescence resonance energy transfer to monitor enzymatic activity, enabling quantification through changes in fluorescence intensity. It is a valuable tool for studying the roles of these metalloproteinases in various biological processes and may facilitate research in cancer biology and inflammatory diseases.
Mca-PLAQAV-Dpa-RSSSR-NH2 192723-42-5 Fluorescent Peptide
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5mg
$190.00
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10mg
$310.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide designed as a substrate for TNF-α converting enzyme (TACE; ADAM17), ADAM9, and ADAM10. This peptide utilizes fluorescence resonance energy transfer to monitor enzymatic activity, enabling quantification through changes in fluorescence intensity. It is a valuable tool for studying the roles of these metalloproteinases in various biological processes and may facilitate research in cancer biology and inflammatory diseases.
Product Information
Catalog NumA76832
FormulaC69H103N23O24
Molecular Weight1638.70
CAS Number192723-42-5
Sequence{Mca}-Pro-Leu-Ala-Gln-Ala-Val-{Dpa}-Arg-Ser-Ser-Ser-Arg-NH2
Sequence shortening{Mca}-PLAQAV-{Dpa}-RSSSR-NH2
SMILESC(C(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CNC2=C(N(=O)=O)C=C(N(=O)=O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CO)=O)CO)=O)CO)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)C)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O)CCC1)C=3C=4C(=CC(OC)=CC4)OC(=O)C3
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