Me-Tet-PEG3-Maleimide is an ADC linker characterized by the presence of three polyethylene glycol (PEG) units and a tetrazine moiety. This compound facilitates a specific inverse electron demand Diels-Alder reaction (iEDDA) with trans-cyclooctene (TCO)-containing compounds, enabling efficient bioconjugation. Additionally, the maleimide functional group exhibits stability in aqueous environments, making this linker suitable for drug delivery applications and the development of antibody-drug conjugates (ADCs).
Me-Tet-PEG3-Maleimide is an ADC linker characterized by the presence of three polyethylene glycol (PEG) units and a tetrazine moiety. This compound facilitates a specific inverse electron demand Diels-Alder reaction (iEDDA) with trans-cyclooctene (TCO)-containing compounds, enabling efficient bioconjugation. Additionally, the maleimide functional group exhibits stability in aqueous environments, making this linker suitable for drug delivery applications and the development of antibody-drug conjugates (ADCs).
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