Me-Tet-PEG4-NHS is an ADC linker featuring four PEG units that facilitates targeted drug delivery. This compound contains a Tetrazine moiety, enabling it to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with trans-cyclooctene (TCO) derivatives. Its key biological activity lies in enhancing the stability and efficacy of antibody-drug conjugates (ADCs), making it suitable for applications in cancer research and therapeutic development.
Me-Tet-PEG4-NHS is an ADC linker featuring four PEG units that facilitates targeted drug delivery. This compound contains a Tetrazine moiety, enabling it to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with trans-cyclooctene (TCO) derivatives. Its key biological activity lies in enhancing the stability and efficacy of antibody-drug conjugates (ADCs), making it suitable for applications in cancer research and therapeutic development.
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