Me-Tet-PEG8-NHBoc is an ADC linker designed for targeted drug delivery applications. This compound features an 8-unit polyethylene glycol (PEG) chain and a tetrazine moiety, enabling it to undergo inverse electron demand Diels-Alder (iEDDA) reactions with trans-cyclooctenes (TCO). Its unique properties make it suitable for use in antibody-drug conjugates (ADCs), facilitating the precise attachment of therapeutic agents to antibodies while enhancing solubility and stability.
Me-Tet-PEG8-NHBoc is an ADC linker designed for targeted drug delivery applications. This compound features an 8-unit polyethylene glycol (PEG) chain and a tetrazine moiety, enabling it to undergo inverse electron demand Diels-Alder (iEDDA) reactions with trans-cyclooctenes (TCO). Its unique properties make it suitable for use in antibody-drug conjugates (ADCs), facilitating the precise attachment of therapeutic agents to antibodies while enhancing solubility and stability.
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