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Me-Tetrazine-Me-Ph-amide-Lys(Boc)-Lys-N3

Catalog No.: A43249
ADC Linker
Me-Tetrazine-Me-Ph-amide-Lys(Boc)-Lys-N3 is an innovative ADC linker that facilitates the construction of antibody-drug conjugates (ADCs). This reagent provides a robust mechanism for site-specific conjugation, enhancing the therapeutic efficacy of ADCs. It is particularly useful in research applications focused on targeted cancer therapies and precision medicine.
Me-Tetrazine-Me-Ph-amide-Lys(Boc)-Lys-N3 2861998-17-4 ADC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMe-Tetrazine-Me-Ph-amide-Lys(Boc)-Lys-N3 is an innovative ADC linker that facilitates the construction of antibody-drug conjugates (ADCs). This reagent provides a robust mechanism for site-specific conjugation, enhancing the therapeutic efficacy of ADCs. It is particularly useful in research applications focused on targeted cancer therapies and precision medicine.
Product Information
Catalog NumA43249
FormulaC31H45N11O7
Molecular Weight683.76
CAS Number2861998-17-4
SMILES[N-]=[N+]=NCCC(NCCCC[C@@H](C(O)=O)NC([C@H](CCCCNC(OC(C)(C)C)=O)NC(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker
Click Chemistry > Tetrazine