Methyltetrazine-Ph-NHS ester is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a tetrazine group that participates in inverse electron demand Diels-Alder (iEDDA) reactions with trans-cyclooctene (TCO) moieties. Its key biological activity lies in enabling targeted protein degradation, providing a valuable tool for researchers exploring protein function and dynamics in cellular systems. Methyltetrazine-Ph-NHS ester is suitable for applications in chemical biology and drug discovery research.
Methyltetrazine-Ph-NHS ester is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a tetrazine group that participates in inverse electron demand Diels-Alder (iEDDA) reactions with trans-cyclooctene (TCO) moieties. Its key biological activity lies in enabling targeted protein degradation, providing a valuable tool for researchers exploring protein function and dynamics in cellular systems. Methyltetrazine-Ph-NHS ester is suitable for applications in chemical biology and drug discovery research.
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