Fig. 1 · Structure
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ML338
Anti-Tuberculosis Agent
ML338 is a selective small molecule inhibitor targeting non-replicating Mycobacterium tuberculosis. It exhibits potent anti-tuberculosis activity, with IC90 and IC99 values of 1 μM and 4 μM, respectively, as determined by colony-forming units (CFU). This compound serves as a valuable tool for investigating essential functions and vulnerabilities of M. tuberculosis under nutrient deprivation conditions. ML338 is ideal for research focused on tuberculosis chemotherapy and the elucidation of bacterial survival mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1630160-25-6 |
| Applications | Anti-Tuberculosis Agent |
| Formula | C17H12ClN5OS |
| Molecular Weight | 369.83 |
| SMILES | ClC1=CC=C(C2=NN=C(SCC3=CN(C4=CC=CC=C4)N=N3)O2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.