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MLCK Peptide

Catalog No.: A66444
CaM Binding Peptide
MLCK Peptide is a high-affinity (pM) calcium/calmodulin (CaM)-binding peptide derived from smooth muscle myosin light-chain kinase. This peptide serves as a valuable tool for studying CaM-mediated signaling pathways and muscle contraction mechanisms. Its reversible binding properties make it suitable for various applications in biochemical and physiological research, particularly in investigations of calcium signaling and muscle physiology.
MLCK Peptide 209251-64-9 CaM Binding Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMLCK Peptide is a high-affinity (pM) calcium/calmodulin (CaM)-binding peptide derived from smooth muscle myosin light-chain kinase. This peptide serves as a valuable tool for studying CaM-mediated signaling pathways and muscle contraction mechanisms. Its reversible binding properties make it suitable for various applications in biochemical and physiological research, particularly in investigations of calcium signaling and muscle physiology.
Product Information
Catalog NumA66444
FormulaC91H156N36O20
Molecular Weight2074.44
CAS Number209251-64-9
SequenceAc-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-NH2
Sequence shorteningAc-RRKWQKTGHAVRAIGRL-NH2
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)C)=O)=O)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3
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