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NAE Inhibitor
In Stock
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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| Caco-2 | IC50 | 0.63 μM | Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells after 48 hours by high content imaging | 10.21203/rs.3.rs-23951/v1 |
| Caco-2 | CC50 | 222.44 μM | Toxicity against Caco-2 cells determined at 48 hours by intracellular ATP concentration using the CellTiter-Glo Luminescent Cell Viability Assay | 10.21203/rs.3.rs-23951/v1 |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1160295-21-5 |
| Applications | NAE Inhibitor |
| Formula | C21H26ClN5O4S |
| Molecular Weight | 480 |
| Synonyms | MLN-4924 HCL |
| SMILES | C1CC2=CC=CC=C2[C@H]1NC3=NC=NC4=C3C=CN4[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N.Cl |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
