Fig. 1 · Structure

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MmpL3-IN-3

MmpL3 Inhibitor

MmpL3-IN-3 is a specific inhibitor of the MmpL3 protein, a vital target in the treatment of tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of 0.1 μM against the Mycobacterium tuberculosis strain H37Rv, indicating potent anti-tubercular activity. Additionally, MmpL3-IN-3 exhibits favorable metabolic stability in mouse liver microsomes, making it a valuable tool for research focused on tuberculosis therapeutics.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1639438-67-7
Applications MmpL3 Inhibitor
Formula C26H33ClN2Si
Molecular Weight 437.09
SMILES
CC1=C(CN2CC[Si](C)(C)CC2)C=C(C3=CC=C(Cl)C=C3)N1C4=CC=C(CC)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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