Fig. 1 · Structure
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MmpL3-IN-5
MmpL3 Inhibitor
MmpL3-IN-5 is a specific inhibitor of the MmpL3 protein, which plays a critical role in the cell wall biogenesis of Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a pMIC of 7.0 μM against the H37Rv strain of Mycobacterium tuberculosis. This compound is valuable for research focused on the development of new therapeutic strategies for tuberculosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1432641-65-0 |
| Applications | MmpL3 Inhibitor |
| Formula | C18H24N2O |
| Molecular Weight | 284.40 |
| SMILES | O=C(C1=CC2=C(C)C=C(C)C=C2N1)NC3CCCCCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.