Mollicellin K is a depsidone derived from the fungus Chaetomium brasiliense, exhibiting significant antimicrobial activity. It demonstrates potent activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 12.5 μM, and strong antimalarial effects against Plasmodium falciparum (IC50 = 1.2 μM). Additionally, Mollicellin K displays antifungal properties against Candida albicans (IC50 = 1.2 μM) and cytotoxic effects against various cancer cell lines, including KB (IC50 = 1.9 μM) and BC1 (IC50 = 6.8 μM). This compound is of interest in research involving infectious diseases and cancer therapeutics.
Mollicellin K is a depsidone derived from the fungus Chaetomium brasiliense, exhibiting significant antimicrobial activity. It demonstrates potent activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 12.5 μM, and strong antimalarial effects against Plasmodium falciparum (IC50 = 1.2 μM). Additionally, Mollicellin K displays antifungal properties against Candida albicans (IC50 = 1.2 μM) and cytotoxic effects against various cancer cell lines, including KB (IC50 = 1.9 μM) and BC1 (IC50 = 6.8 μM). This compound is of interest in research involving infectious diseases and cancer therapeutics.
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