Moracin G

Catalog No.: A64339
Apoptosis Inducer
Moracin G is an apoptosis inducer that acts as a kinase modulator and receptor ligand. It forms stable interactions with key proteins, including AKT1, COX2, and Estrogen receptor 1, while competitively inhibiting specific kinase activity. By binding to MELK, Moracin G disrupts cell cycle regulation, leading to the impairment of cancer cell survival and proliferation, as well as the induction of apoptosis. This compound is relevant in research focusing on periodontitis and breast cancer.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMoracin G is an apoptosis inducer that acts as a kinase modulator and receptor ligand. It forms stable interactions with key proteins, including AKT1, COX2, and Estrogen receptor 1, while competitively inhibiting specific kinase activity. By binding to MELK, Moracin G disrupts cell cycle regulation, leading to the impairment of cancer cell survival and proliferation, as well as the induction of apoptosis. This compound is relevant in research focusing on periodontitis and breast cancer.
Product Information
Catalog NumA64339
FormulaC19H16O4
Molecular Weight308.33
CAS Number73338-86-0
SMILESOC1=CC(O)=CC(C2=CC(C=CC3=C4CC=C(C)CO3)=C4O2)=C1
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