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Biological Activity
MRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.7 mL | 98.52 mL | 197.04 mL |
| 0.5 mM | 3.94 mL | 19.7 mL | 39.41 mL |
| 1 mM | 1.97 mL | 9.85 mL | 19.7 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 507.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21650 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2080306-21-2 |
| Formula | C25H36Cl2N6O |
| M. Wt | 507.5 |
| Purity | >98% |
| Synonyms | MRT 68921, MRT-68921 |
| SMILES | [H]Cl.O=C(C1CCC1)NCCCNC2=NC(NC3=CC4=C(CN(C)CC4)C=C3)=NC=C2C5CC5.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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