Fig. 1 · Structure
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MRV03-068
ClbP Inhibitor
MRV03-068 is a selective inhibitor of colibactin-activated peptidase (ClbP), effectively blocking the genotoxic effects of colibactin on eukaryotic cells. This compound is particularly valuable in colorectal cancer research, providing insights into the role of microbial metabolites in tumorigenesis. Its targeted inhibition of ClbP facilitates investigations into the molecular mechanisms underlying colibactin-induced cellular damage.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2797066-17-0 |
| Applications | ClbP Inhibitor |
| Formula | C20H25BN2O4 |
| Molecular Weight | 368.23 |
| SMILES | O=C(C1=CC(C=CC=C2)=C2C=C1)N[C@H](CC(N)=O)B3OC(C)(C)C(C)(C)O3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.