Documents & Downloads

MsbA-IN-1

MsbA Inhibitor

MsbA-IN-1 is a potent inhibitor of the MsbA transporter, exhibiting an IC50 value of 4 nM. This compound demonstrates significant antimicrobial activity against wild-type Escherichia coli, with a minimum inhibitory concentration (MIC) of 79 μM. MsbA-IN-1 is characterized by its ability to effectively permeate the intact outer membrane of Gram-negative bacteria, allowing it to inhibit MsbA function. This makes it a valuable tool for research into antibiotic resistance and efflux pump mechanisms.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2918334-61-7
Applications	MsbA Inhibitor
Formula	C₂₃H₁₈Cl₂FNO₃
Molecular Weight	446.30
SMILES	O=C(O)/C=C/C1=C(C2CC2)C3=CC(O[C@H](C4=C(Cl)C=CC(F)=C4Cl)C)=CC=C3N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.