Fig. 1 · Structure

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MsbA-IN-2

MsbA Inhibitor

MsbA-IN-2 is a potent inhibitor of the MsbA transporter, exhibiting an IC50 value of 2 nM in E. coli. This compound demonstrates significant efficacy in blocking lipopolysaccharide transport, making it a valuable tool for research into bacterial membrane biology and antibiotic resistance mechanisms. MsbA-IN-2 is suitable for studies aimed at understanding MsbA function and the development of new antimicrobial therapies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2909443-16-7
Applications MsbA Inhibitor
Formula C23H19Cl2NO3
Molecular Weight 428.31
SMILES
O=C(O)/C=C/C1=C(C2CC2)C3=CC(O[C@H](C4=C(Cl)C=CC=C4Cl)C)=CC=C3N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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