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Mt KARI-IN-1

Mt KARI Inhibitor

Mt KARI-IN-1 is a potent inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) with a Ki value of 3.06 μM. This compound demonstrates significant potential in the study of tuberculosis by effectively disrupting essential metabolic pathways in the bacterium. Its inhibitory activity positions Mt KARI-IN-1 as a valuable tool for research aimed at developing new therapeutic strategies against Mycobacterium tuberculosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2987760-64-3
Applications	Mt KARI Inhibitor
Formula	C₁₄H₁₁N₅O₄S₂
Molecular Weight	377.40
SMILES	COC1=CC=C(C=C1)NC(NC2=NN=C(S2)C3=CC=C(S3)[N+]([O-])=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.